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As a result, those involved in the fight against HIV began to emphasize aspects such as preventing transmission from mother to child, or the relationship between HIV and poverty, inequality of the sexes, and so on, rather than emphasizing the need to prevent transmission by unsafe sexual practices or drug injection.

This change in emphasis resulted in more funding, but was not effective in preventing a drastic rise in HIV prevalence.

Countries in North Africa and the Horn of Africa have significantly lower prevalence rates, as their populations typically engage in fewer high-risk cultural patterns that have been implicated in the virus' spread in Sub-Saharan Africa.

Southern Africa is the worst affected region on the continent.

Among these are combination prevention programmes, considered to be the most effective initiative, such as the abstinence, be faithful, use a condom campaign and the Desmond Tutu HIV Foundation's outreach programs. Botswana, for example, lost 17% of its healthcare workforce due to AIDS between 19. The toll of HIV and AIDS on households can be very severe. [I]t is often the poorest sectors of society that are most vulnerable.... AIDS causes the household to dissolve, as parents die and children are sent to relatives for care and upbringing. Much happens before this dissolution takes place: AIDS strips families of their assets and income earners, further impoverishing the poor. Upon a family member becoming ill, the role of women as carers, income-earners and housekeepers is stepped up. As parents and family members become ill, children take on more responsibility to earn an income, produce food, and care for family members. [M]ore children have been orphaned by AIDS in Africa than anywhere else.

According to a 2013 special report issued by the Joint United Nations Programme on HIV/AIDS (UNAIDS), the number of HIV positive people in Africa receiving anti-retroviral treatment in 2012 was over seven times the number receiving treatment in 2005, "with nearly 1 million added in the last year alone". has caused immense human suffering in the continent. They are often forced to step into roles outside their homes as well. Older people are also heavily affected by the epidemic; many have to care for their sick children and are often left to look after orphaned grandchildren. It is hard to overemphasise the trauma and hardship that children ... Many children are now raised by their extended families and some are even left on their own in child-headed households. HIV and AIDS are having a devastating effect on the already inadequate supply of teachers in African countries.... in 2006 it was estimated that around 45,000 additional teachers were needed to make up for those who had died or left work because of HIV.... has been among adults aged between 20 and 49 years.

The virus likely moved from primates to humans when hunters came into contact with the blood of infected primates.

As of 2011, HIV has infected at least 10 percent of the population in Botswana, Lesotho, Malawi, Mozambique, Namibia, South Africa, Swaziland, Zambia, and Zimbabwe.

In response, a number of initiatives have been launched in various parts of the continent to educate the public on HIV/AIDS. not been confined to the health sector; households, schools, workplaces and economies have also been badly affected. In sub-Saharan Africa, people with HIV-related diseases occupy more than half of all hospital beds. [L]arge numbers of healthcare professionals are being directly affected.... epidemic adds to food insecurity in many areas, as agricultural work is neglected or abandoned due to household illness. Almost invariably, the burden of coping rests with women.

Some areas of the world were already significantly impacted by AIDS, while in others the epidemic was just beginning.

The virus is transmitted by bodily fluid contact including the exchange of sexual fluids, by blood, from mother to child in the womb, and during delivery or breastfeeding.

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One of the most formative explanations is the poverty that dramatically impacts the daily lives of Africans.

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